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熱門詞: 進口電動溫度調(diào)節(jié)閥結(jié)構(gòu)圖|進口電動溫度調(diào)節(jié)閥數(shù)據(jù)表進口電動高溫調(diào)節(jié)閥-德國進口電動高溫法蘭調(diào)節(jié)閥進口電動蒸汽調(diào)節(jié)閥-德國進口電動蒸汽調(diào)節(jié)閥

Aurora Scientific代理1700A,肌原纖維測試系統(tǒng),Myofibril System

價  格:詢價

產(chǎn)  地:加拿大更新時間:2020-10-15 16:29

品  牌:奧羅拉型  號:1700A

狀  態(tài):正常點擊量:1551

400-006-7520
聯(lián)系我時,請說明是在上海非利加實業(yè)有限公司上看到的,謝謝!

上海非利加實業(yè)有限公司

聯(lián) 系 人: 上海非利加實業(yè)有限公司

電   話: 400-006-7520

傳   真: 400-006-7520

配送方式: 上海自提或三方快遞

聯(lián)系我時請說在上海非利加實業(yè)有限公司上看到的,謝謝!



完整的透化肌原纖維測試系統(tǒng)

溫度調(diào)節(jié)組織浴

簡單安裝在倒置顯微鏡上

計算機控制的電動XYZ微定位平臺

包括緩沖閥和解決方案切換器控制器

控制和測量力,長度和肌節(jié)間距

測量力-pCa,kTr,剛度,長度 - 張力和力 - 速度關(guān)系

與Aurora Scientific 900B高速視頻Sarcomere長度系統(tǒng)(HVSL)無縫連接

參考文獻:

Schappacher-Tilp, Gudrun et al. “Computing Average Passive Forces in Sarcomeres in Length-Ramp Simulations .” PLoS Computational Biology 12.6 (2016): e1004904.

Cornachione, Anabelle S. et al. “The increase in non-cross-bridge forces after stretch of activated striated muscle is related to titin isoforms.” American Journal of Physiology - Cell Physiology 310.1 (2016): C19-C26.

Leite, Felipe S. et al. “Reduced passive force in skeletal muscles lacking protein arginylation.” American Journal of Physiology - Cell Physiology 310.2 (2016): C127-135.

Powers, Krysta et al. “Decreased force enhancement in skeletal muscle sarcomeres with a deletion in titin.” Journal of Experimental Biology 219.9 (2016): 1311-1316.

Minozzo, Fábio C., David Altman, and Dilson E. Rassier. “MgADP activation contributes to force enhancement during fast stretch of isolated skeletal myofibrils.” Biochemical and Biophysical Research Communications 463.4 (2015): 1129-1134.

Philippou, Anastassios et al. “Masticatory muscles of mouse do not undergo atrophy in space.” The FASEB Journal 29.7 (2015): 2769-2779.

Rassier, Dilson, and Aleksander Labuda. “Method and apparatus for measuring cantilever deflection in constrained spaces.” (2014): U.S. Patent No. 8,667,611.

Cornachione, Anabelle S. et al. “Arginylation of Myosin Heavy Chain Regulates Skeletal Muscle Strength.” Cell Reports 8.2 (2014): 470-476.

Yamada, Takashi et al. “Nitrosative modifications of the Ca2+ release complex and actin underlie arthritis-induced muscle weakness.” Annals of the Rheumatic Diseases 74.10 (2014): 1907-1914.

Ribeiro, Paula A.B. et al. “Contractility of myofibrils from the heart and diaphragm muscles measured with atomic force cantilevers: Effects of heart-specific deletion of arginyl-tRNA-protein transferase.” International Journal of Cardiology 168.4 (2013): 3564-3571.

Labuda, Aleksander et al. “Optical detection system for probing cantilever deflections parallel to a sample surface.” Review of Scientific Instruments 82.1 (2011): 013701.

Rassier, Dilson E. “Striated Muscles: From Molecules to Cells.” Advances in Experimental Medicine and Biology Muscle Biophysics (2010): 1-6.

Joumaa, Venus, Walter Herzog, and Dilson E. Rassier. “904-Plat Critical Sarcomere Length Extension and Phase Transition Of Force During Lengthening Of Skeletal Muscle Myofibrils.” Biophysical Journal 94.2 Supplement (2008): 305-307.


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產(chǎn)品介紹

1700A肌原纖維系統(tǒng)是第***個商業(yè)化的肌原纖維系統(tǒng),專門用于測量單個肌原纖維激活產(chǎn)生的納米牛頓力。這是***個完整的測試系統(tǒng),包括表征肌原纖維收縮所需的所有硬件。1700A包括:470A肌原纖維原子力顯微鏡(AFM)傳感器,340A壓電長度控制器,溫控浴槽,470A-XYZ電動平移臺,820A雙XYZ運動控制器,用于計算機控制AFM懸臂和玻璃針定位,溶液閥控制器,解決方案切換電機驅(qū)動器和我們的實時Linux 600A數(shù)據(jù)采集系統(tǒng)。

470 Myofibril AFM傳感器利用原子力顯微鏡和光束偏轉(zhuǎn)方法測量單個肌原纖維激活產(chǎn)生的納米牛頓力。肌原纖維固定在AFM懸臂和玻璃針之間,AFM懸臂用作高靈敏度力傳感器,玻璃針連接到340A壓電長度控制器??刂崎L度和測量力使1700A肌原纖維系統(tǒng)能夠提供肌原纖維的完整機械表征。根據(jù)所使用的懸臂,滿量程力為1-10μN,驚人的分辨率為1nN。

1700A包含溫度調(diào)節(jié)組織浴以及緩沖液交換系統(tǒng)的控制,這是快速激活任何肌原纖維的關(guān)鍵組分。該設(shè)備可以很容易地安裝在倒置顯微鏡上,為浴缸和肌原纖維提供方便和清晰的通道。

用于肌原纖維機械表征的可定制方案可以使用我們的600A數(shù)據(jù)采集系統(tǒng)進行,當與我們的可選900B / 901C VSL肌節(jié)長度測量軟件結(jié)合使用時,研究人員可以控制和測量長度,力和肌節(jié)長度。




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