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歐蒙 EUROIMMUN    
歐蒙醫(yī)學(xué)實(shí)驗(yàn)診斷股份公司創(chuàng)建于1987年9月，現(xiàn)總部位于德國呂貝克市，在Gro? Gr?nau，Rennersdorf和Pegnitz設(shè)有分部。歐蒙公司在加拿大（米西索加）、中國（北京，杭州）、英國（新港）、意大利（帕多瓦）、黎巴嫩（貝魯特）、波蘭（弗羅茨瓦夫）、瑞士（洛桑）、新加坡、南非（開普敦）、土耳其（伊斯坦布爾）、美國（新澤西州）設(shè)有分公司，現(xiàn)有員工近2000人。公司已取得ISO認(rèn)證（EN ISO 9001:2000, EN ISO 13485:2003, ISO 13485/CMDCAS）。

歐蒙公司是醫(yī)學(xué)實(shí)驗(yàn)診斷試劑的生產(chǎn)企業(yè)，在自身免疫性疾病、感染性疾病和變態(tài)反應(yīng)性疾病的血清抗體檢測領(lǐng)域位于世界前沿。歐蒙公司產(chǎn)品采用的實(shí)驗(yàn)方法主要有間接免疫熒光法、微孔板ELISA法、各種印跡技術(shù)（免疫印跡法、歐蒙斑點(diǎn)法、歐蒙印跡法和EUROLINE-WB）和分子生物學(xué)技術(shù)?；谝言谌蚍秶@得專利的完美生產(chǎn)工藝和微量檢測技術(shù)，歐蒙公司正成為醫(yī)學(xué)實(shí)驗(yàn)診斷領(lǐng)域的世界領(lǐng)先制造商。

生物薄片（BIOCHIPs ）是歐蒙公司眾多創(chuàng)新技術(shù)之一：將細(xì)胞或組織切片包被在極薄的蓋玻片上，再用自動(dòng)化機(jī)械將其切割成毫米大小的片段，隨后用全自動(dòng)的儀器將它們固定在載片上。這種生物薄片技術(shù)可使實(shí)驗(yàn)分析高度微量化和標(biāo)準(zhǔn)化。生物薄片馬賽克（BIOCHIP Mosaics?）可將30種或更多的不同組織、細(xì)胞基質(zhì)或性質(zhì)明確的抗原（EUROPLUS?）進(jìn)行組合，僅需要簡單的實(shí)驗(yàn)溫育，即可獲得詳盡的自身抗體譜信息。

歐蒙酶聯(lián)免疫分析（ELISA）試劑采用經(jīng)先進(jìn)生物技術(shù)純化的抗原作為檢測基質(zhì)，很多抗原是由歐蒙分子生物學(xué)實(shí)驗(yàn)室合成。歐蒙ELISA具有穩(wěn)定性好、操作簡單、溫育時(shí)間短和適于自動(dòng)化等優(yōu)點(diǎn)。試劑盒中大多數(shù)成分可直接使用，并且不同批次之間可互換。歐蒙公司現(xiàn)可提供世界上最多種類的用于自身免疫性疾病和感染性疾病診斷的酶聯(lián)免疫檢測試劑。

歐蒙斑點(diǎn)法(EUROASSAY) 和歐蒙印跡法(EUROLINE)是歐蒙公司的革新技術(shù)。其遵循ELISA法的實(shí)驗(yàn)原理，并使用滴定平板技術(shù)和生物薄片技術(shù)：將純化的抗原平行印在膜條上的指定位置。溫育后，不需用其它設(shè)備就可目測結(jié)果。歐蒙斑點(diǎn)法和歐蒙印跡法特別適合于間接免疫熒光法中顯微鏡下不能確定的抗體分型，也適合于無精密實(shí)驗(yàn)設(shè)備的實(shí)驗(yàn)室使用。歐蒙公司還提供多種免疫印跡法試劑盒和相應(yīng)試劑，用于確認(rèn)免疫熒光法和ELISA的陽性結(jié)果以及自身免疫性疾病、感染性疾病和變態(tài)反應(yīng)性疾病診斷中的疑難樣本；并且，歐蒙已研發(fā)出新型電泳系統(tǒng)用于精確分離具有診斷意義的相關(guān)蛋白條帶，同時(shí)提供批特異的參照膜條用于檢測結(jié)果的分析。結(jié)果分析軟件EURO-LineScan可使以膜為載體的檢測系統(tǒng)實(shí)現(xiàn)結(jié)果的計(jì)算機(jī)自動(dòng)判讀，簡化了大量標(biāo)本的結(jié)果分析。

歐蒙公司卓越的技術(shù)優(yōu)勢不僅體現(xiàn)在生產(chǎn)和銷售醫(yī)學(xué)實(shí)驗(yàn)診斷產(chǎn)品上，也表現(xiàn)于公司參考實(shí)驗(yàn)室應(yīng)用這些產(chǎn)品進(jìn)行高級(jí)鑒別診斷上。此參考實(shí)驗(yàn)室建立了德國乃至世界范圍內(nèi)統(tǒng)一的自身免疫性疾病實(shí)驗(yàn)室檢測標(biāo)準(zhǔn)。該實(shí)驗(yàn)室的檢測項(xiàng)目還覆蓋了感染性疾病和變態(tài)反應(yīng)性疾病的血清學(xué)診斷，每天為來自德國和其它國家的上百份血清樣品進(jìn)行免費(fèi)檢測。這樣不僅有助于歐蒙客戶獲得準(zhǔn)確的實(shí)驗(yàn)結(jié)果，還保證了客戶實(shí)驗(yàn)室的高水準(zhǔn)?？蛻暨€可從公司的資深專家那里獲得豐富的技術(shù)信息，并與他們就血清學(xué)領(lǐng)域中的問題進(jìn)行深入討論。歐蒙公司新成立了質(zhì)量保證研究所，負(fù)責(zé)組織公正的質(zhì)量評(píng)估并就質(zhì)量管理中的問題提出建議。另外，歐蒙公司還建立了實(shí)驗(yàn)主要從事基礎(chǔ)研究的免疫學(xué)研究所。

截止到2010年10月，歐蒙（德國）員工中有150名大學(xué)畢業(yè)生，他們中有生物學(xué)家、生化學(xué)家、化學(xué)家、工程師和臨床醫(yī)生（其中48人獲得博士學(xué)位）。歐蒙還有103名與公司業(yè)務(wù)相應(yīng)的醫(yī)學(xué)技術(shù)人員和81名生物化學(xué)/化學(xué)實(shí)驗(yàn)室技術(shù)員?，F(xiàn)在有55個(gè)年輕人在公司接受培訓(xùn)，他們將來承擔(dān)生物實(shí)驗(yàn)室技術(shù)員、職員、IT專家、電子系統(tǒng)技師、儀器和系統(tǒng)電子技師和工程機(jī)械師等工作。

歐蒙公司致力于引導(dǎo)客戶使用先進(jìn)的技術(shù)，支持客戶使用對(duì)診斷有幫助的產(chǎn)品，努力淡化商業(yè)行為。歐蒙產(chǎn)品的成功推廣基于充滿朝氣并具有競爭力的銷售團(tuán)隊(duì)、優(yōu)質(zhì)的信息資料、詳細(xì)易讀的產(chǎn)品說明書和在專業(yè)雜志上刊登富有科學(xué)性、普及性的廣告宣傳。公司使用最先進(jìn)的編輯制作方法和數(shù)碼成像系統(tǒng)自己制作各種宣傳資料，重要的出版物和產(chǎn)品彩頁已翻譯成多種語言。歐蒙公司在互聯(lián)網(wǎng)上的主頁：www.euroimmun.com，歡迎全球朋友訪問。

目前世界上已有3000多家實(shí)驗(yàn)室在使用歐蒙公司的產(chǎn)品，其中400多家在德國。歐蒙公司正日益發(fā)展壯大。盡管德國的診斷試劑市場停滯不前并且競爭激烈，但歐蒙公司仍保持強(qiáng)勁的發(fā)展勢頭。隨著越來越多的產(chǎn)品銷往世界各地，歐蒙在德國市場獨(dú)樹一幟。歐蒙的產(chǎn)品以其優(yōu)秀品質(zhì)占據(jù)著世界領(lǐng)先地位。

EUROIMMUN produces a wide range of reagents for medical laboratory diagnostics. The main focus is on test systems for antibodies in patient serum. These allow highly sensitive and specific diagnosis of autoimmune diseases, infectious diseases and allergies.

Test methods are predominantly indirect immunofluorescence, microplate ELISA, various blot techniques (Westernblot, EUROASSAY, EUROLINE, EUROLINE-WB), RIA and all molecular biology techniques. EUROIMMUN also offers a comprehensive range of automation solutions. With innovative and patented production methods and microanalysis techniques, EUROIMMUN is one of the world's leading manufacturers of medical laboratory diagnostics.

EUROIMMUN was founded in September 1987 and today has its headquarters in Luebeck, Germany. German branches are situated in Gross Groenau near Luebeck (Schleswig Holstein), Dassow (Mecklenburg-Western Pomerania), Rennersdorf (Upper Lusatia, Saxony) and in Pegnitz (Upper Franconia, Bavaria). Further EUROIMMUN AG subsidiaries can be found in Canada (Mississauga), China (Beijing, Hangzhou), Great Britain (Wimbledon), Italy (Padua), Poland (Wroc--?aw), Switzerland (Lucerne), Singapore, South Africa (Cape-town), Brazil (Porto Alegre), Turkey (Istanbul) and the USA (New Jersey). At present EUROIMMUN has 944employees in Germany, 1311 worldwide. The company is ISO-certified (EN ISO 9001:2008, EN ISO 13485:2003/CMDCAS).

EUROIMMUN produces reagents for medical laboratory diagnostics. In the foreground are test systems for the determination of various antibodies in patient serum in the diagnosis of autoimmune diseases, infectious diseases and allergies. The test methods employed are predominantly indirect immunofluorescence, microplate ELISA, various blot techniques (Westernblot, EUROASSAY, EUROLINE, EUROLINE-WB) and all molecular biology techniques. The company is based on worldwide-patented state-of-the-art production methods and microanalysis techniques and is one of the world’s leading manu-facturers of medical laboratory diagnostics.

The BIOCHIPs are one of EUROIMMUN’s many inventions: paper-thin sheets of glass are coated with cells or tissue sections and then cut automatically into millimetre-sized fragments which are subsequently glued onto slides using a fully automated device. This BIOCHIP technology allows extreme miniaturization and standardization of immun-bio-chemical analyses. With BIOCHIP Mosaics?made from 30 or more different organ sections, cell substrates or defined antigens (EUROPLUS?) only mini-mum incubation efforts are necessary to obtain a detailed antibody profile.

In EUROIMMUN enzyme immunoassays (ELISAs) defined antigens, purified using state-of-the-art biotechnological processes, are employed as the antigen substrate. Some of these antigens are synthesized in the company’s molecular biology laboratories. EUROIMMUN ELISA are characterized by their excellent stability, simple handling and short incubation times, and they are ideal for automated use. All reagents are delivered ready-to-use and are exchangeable between different lots. EUROIMMUN offers the largest and most differentiated arsenal of enzyme immunoassays worldwide for the diagnosis of autoimmune and infectious diseases.

The innovative procedures EUROASSAY and EUROLINE developed by EUROIMMUN follow the same test principle as the ELISA methods, with the use of the BIOCHIP technology. At EUROIMMUN purified antigens are printed in parallel lines at defined positions on membrane strips. Following incubation, users can evaluate results visually without additional equipment. These reagents allow in particular the differentiation of antibodies that are not clearly defined microscopically by indirect immunofluorescence. EUROASSAY and EUROLINE are also em-ployed in laboratories where no sophisticated laboratory instruments are available. EUROIMMUN produces an extensive range of Westernblot strip test systems and corres-ponding reagents for confirmation of positive fluorescence and ELISA results as well as clarification of difficult-to-interpret results in autoimmune diagnostics, infectious serology and allergology. Refined electrophoretical processes have been developed to allow the precise separation of diagnostically relevant proteins from one another. Lot-specific evalu-ation templates are produced for the evaluation of band patterns. The program ”EURO-LineScan“ enables fully automated evaluation of membrane-based test systems and simplifies the archiving of results with large sample series.

One of the company’s main strengths is its technical expertise. This encompasses not just the manufacture and sale of medical laboratory diagnostics, but also the diagnostic application of the products in a reference laboratory which provides highly differential diagnostics. This reference laboratory has set standards in Germany, and worldwide is unequalled in the whole field of autoimmune diagnostics. The diagnostic spectrum of the laboratory also covers the areas of infectious serology and serological allergy diagnostics. The reference laboratory receives hundreds of serum samples daily from all over Germany as well as from many other countries. It helps EUROIMMUN customers to secure their results: a large proportion of serum samples sent to EUROIMMUN for evaluation are analysed free of charge in order to maintain high standards in the laboratories of EUROIMMUN customers. Customers can obtain further technical information from experienced scientists in the company, with whom they can also discuss serological problem cases. The “Institute for Quality Assurance”, an institution newly founded by EUROIMMUN, organises unbiased quality assessments and provides advice in the area of quality management. Moreover EUROIMMUN has established the “Institute for experimental Immunology”, which is engaged in basic research.

In October 2012 the EUROIMMUN workforce included 170 university and college graduates, among these biologists, biochemists, chemists, engineers and medical doctors (48 of them holding a doctor’s degree). Medical technicians are particularly strongly represented with 111 people, corresponding to EUROIMMUN’s activities, as well as biology/chemistry laboratory technicians (81). At present the company is training 51 young people as biology laboratory assistants, industrial clerks, office communication clerks, IT specialists, IT clerks, electronic system technicians, electronic technicians for devices and systems, industrial mechanics, cooks, computer scientists and business economists (dual system).

At EUROIMMUN great value is placed on advising customers and prospective customers in a factual, technical and commercially restrained manner and fully supporting them in the use of our diagnostically demanding products. EUROIMMUN products are backed by an energetic and competent sales force, qualified information material, didactic test instructions and scientifically based, but nevertheless understandable advertisements in technical journals. Advertising material is produced in-house using the latest desktop publishing methods, right up until the fully digitalised ready-for-exposure documents. The most important publications and posters are translated into many languages.

Over 3,000 laboratories worldwide use EUROIMMUN diagnostics: 400 of these are in Ger-many. The company’s development is shaped by continuous growth. Although the diagnostic market in Germany stagnated and has become particularly strongly competitive, EURO-IMMUN has been able to continue its strong expansion. The company is achieving an ever increasing independence from the German market, since more and more products are sold abroad. With their quality and standardization, EUROIMMUN products are capturing the leading position in the world.